MyBioSource.com's SEL1L Antibody, HRP conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, and ELISA. The SEL1L Antibody, HRP conjugated was generated using SEL1L, and SEL1L adaptor subunit of ERAD E3 ubiquitin ligase as the antigen and it reacts with Human.
Description
Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16186509). Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling